A new process of synthesis of menthyl nicotinate, with an industrially acceptable final yield of menthyl nicotinate at high purity, easily accomplished in a relatively short time and without the use of any type of solvent or of precursors or intermediate compounds or materials that are hazardous or difficult to handle or store.

LIST OF PATENTS:

US 10,654,806 B2; Europe EP 3 464 241 B1; Italy 102016000058282; Japan 6648311; Korea 10-2159227; Russia 2018146596; China 201780013935.5; India 201817040202.

Compositions for topical use including menthyl nicotinate as primary active ingredient, in such a dose as to stimulate in a subject the sexual response, preferably in such a dose as to maximize this response in a relative short time, and at least one appropriate lipophilic vehicle so as to solubilize the menthyl nicotinate and allow a rapid absorption thereof in the epithelial tissues ofthe female and/or male erogenous zones.